“We do not recommend buying off-the-shelf taurine or drinking energy drinks,” said Yadav. However, taurine’s effect on aging needs to be verified in human studies, said Yadav and Wackerhage. They also suggest that restoring depleted levels through supplements, or possibly even exercise, is possible. Taken together, the data all point to the possibility that taurine can play a role in slowing aging-or, at the very least, in making animals healthier as they get older. After a group of people in the large data set were asked to cycle on a stationary bike to exhaustion, their taurine levels rose. Wackerhage then investigated how taurine levels are affected by exercise. “That showed taurine levels in the blood are associated with disease,” he said. The study also included data on people’s health outcomes and showed that people with higher taurine levels tended to be healthier-with lower levels of blood glucose, cholesterol, and inflammation, all of which are associated with aging-compared to those with lower taurine levels. He took advantage of an earlier, large study of 12,000 people in which other scientists had collected blood from the participants and therefore had data on a variety of metabolites, including taurine. Wackerhage built off of Yadav’s work in the various animal species and looked at how taurine levels might be related to aging in people. “It’s almost too good to be true,” said his collaborator Henning Wackerhage, professor of exercise biology at the Technical University of Munich in Germany. Read More: Magnesium Supplements Are a Buzzy New Sleep and Anxiety Aid. Yadav found similar life-extending and health-promoting effects of taurine supplementation in worms and monkeys, the latter of which most closely resemble people. “Taurine made the animals live healthier and longer lives because it was affecting all the major hallmarks of aging.” “Whatever we checked, the taurine-supplemented mice were healthier and appeared younger than controls,” Yadav said. The longer lifespan was also a healthier one for the animals. Next, they fed older animals taurine supplements to restore these levels to what they were when the mice were younger, and found that the supplemented mice lived on average 10% to 12% longer than old mice who hadn’t received taurine supplements. In a series of experiments that extended over 11 years, the team, led by Vijay Yadav from the National Institute of Immunology in New Delhi, India, first documented that circulating levels of taurine in the blood of mice declined with age.
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